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Aug 15, 2023Liked by Michael Coleman, Ph.D.

A well-written and insightful article. I find most interesting the coniguity of science research to the cause and perhaps prevention of aging, as aging is an inevitable part of life.

Of course diet and exercise plays a huge role in health and longevity, but i wonder how calorie restriction should be utilized in order to prevent mTOR. Is CR just a scientific term for prevention of obesity/being over-weight?

Something else to note, the FDA doesnt approve/test a large majority of supplements being sold to consumers. It's important to obtain supplements such as taurine and resveratrol from trusted sources so as not to be spending money on vegetable capsules filled with empty calories.

One final thought, for the conspiracy theorists... There is a population crisis on Earth, most notably in the Asian continent. Immigration from Asia/Middle East has swept over the world. Would longer lifespans speed up the over population of Earth? Furthermore, life longevity would not look desire-able to the people who run the world (whether they be billionaires or lizard people - depending on the conspirator). How would the US government, secret organizations, or 'lizard people' hinder the research and preventions of aging? There are already conspiracies towards Bill Gates' "Apeel" program (chemical coating over fruits and veggies) with supposed eugenic properties.

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Aug 15, 2023·edited Aug 15, 2023Liked by Michael Coleman, Ph.D.

Thanks for this excellent article!

Resveratrol was tested 3 times in the NIH Interventions Testing Program (ITP) and failed to show any benefit on lifespan (contrary to acarbose, rapamycin and a few others): https://www.nia.nih.gov/research/dab/interventions-testing-program-itp/supported-interventions

Do you know by any chance if someone has already submitted a proposal to test taurine in the ITP? (See: https://www.nia.nih.gov/research/dab/interventions-testing-program-itp/application-instructions ) Anyone can request a test so I may well do it...

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Jul 25, 2023Liked by Michael Coleman, Ph.D.

Excellent article Dr. Coleman.

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